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Scientists hunt down genes behind humankind's big brain
JAY GORY, MANAGING EDITOR, science
By Will Dunham WASHINGTON (Reuters) - Scientists have pinpointed three genes that may have played a pivotal role in an important milestone in human evolution: the striking increase in brain size that facilitated cognitive advances that helped define what it means to be human. The three nearly identical genes, as well as a fourth nonfunctional one, are called NOTCH2NL genes, arising from a gene family dating back hundreds of millions of years and heavily involved in embryonic development. The NOTCH2NL genes are particularly active in the reservoir of neural stem cells of the cerebral cortex, the brain's outer layer responsible for the highest mental functions such as cognition, language, memory, reasoning and consciousness. read more
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