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Gene editing tool may raise cancer risk in cells, scientists warn
JAY GORY, MANAGING EDITOR, science
By Kate Kelland LONDON (Reuters) - A gene-editing technology that is being explored by scientists worldwide as a way of removing and replacing gene defects might inadvertently increase cancer risk in cells, scientists warned on Monday. Researchers from the Britain's Cambridge University and Sweden's Karolinska Institute said more research needs to be done to assess whether using CRISPR-Cas9 – a type of molecular "scissors" that make gene editing a possibility – might lead to the development of treatments that have added cancer risk. The team, led by Jussi Taipale at Cambridge, found that CRISPR-Cas9 triggers a mechanism designed to protect cells from DNA damage, making gene editing more difficult. read more
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